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Computational Drug Discovery

All research in Computational Drug Discovery — 3 reports.

38/100 Avoid Simulations Plus: A Credible Drug-Modeling Specialist, Now Priced as a Near-Cash Deal Stock Simulations Plus builds scientifically trusted drug-development modeling software (GastroPlus, MonolixSuite, ADMET Predictor, DILIsym), but its revenue mix has drifted toward lower-margin services since the 2024 Pro-ficiency acquisition, which pulled FY2025 gross margin to 58% and triggered a $77.2m impairment. On 2026-06-26 the equity trades as a near-cash event security: Altaris' agreed $18.50-per-share takeout caps upside just above the $18.14 close, while a broken deal would reopen real downside. Rating Avoid: a thin-spread cash-deal security whose unresolved software-mix question still sits underneath the transaction. Simulations Plus, Inc.SLP · USComputational Drug DiscoveryJun 26, 2026 47/100 Watch Certara Deep Dive: A Biosimulation Software and Services Platform Embedded in Regulatory Workflows Certara is a biosimulation software and regulatory-science services provider whose software is used by 20 global regulatory agencies and helps drug developers shorten R&D and approval pathways through modeling and simulation. Software revenue grew nearly 18% year over year in 2025, but the larger services business saw revenue fall 4% and bookings decline 14% in Q1 2026, while full-year core growth guidance is only 0%–4%. Research rating Watch: the software moat remains intact, but the services drag and restructuring execution still need quarterly proof. Certara, Inc.CERT · USComputational Drug DiscoveryJun 12, 2026 43/100 Hold Schrödinger (SDGR) Zen Horizon Research Report Schrödinger is a physics-based computational drug discovery platform built around FEP+, a gold-standard method, with 19 of the world's top 20 pharma companies as software customers and additional upside from internal and partnered pipelines plus repeat equity monetizations. Its current market value is about $1.1 billion, with roughly $300 million of net cash, while the stock is down 86% from its 2021 peak. Research rating Hold: a real platform with a hard moat and cheap parts, but slower software growth and limited near-term catalysts keep the risk-reward balanced. Schrödinger, Inc.SDGR · USComputational Drug DiscoveryJun 5, 2026